Eagen Lab, Summer 2023
Lab Members
Kyle Eagen, Ph.D.
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Kyle is an Assistant Professor in the Department of Molecular and Cellular Biology at Baylor College of Medicine. He received his B.S. degree in Biological Sciences with a concentration in Biochemistry from Cornell University. He obtained his Ph.D. in Biophysics from Stanford University where he worked with Roger Kornberg studying chromatin and chromosome structure. After completing graduate training, Kyle began his independent career in 2017 as the inaugural Feinberg Fellow at the Northwestern University Feinberg School of Medicine. In 2021 he joined the faculty of Baylor College of Medicine. He is a recipient of an NIH Director's Early Independence Award, a CPRIT Scholar in Cancer Research Award, and an Alex's Lemonade Stand Foundation for Childhood Cancer R Accelerated Award.
Ivo received his BSc in Biochemistry from the University of Sheffield, where he used X-ray crystallography to investigate the use of triazole-phosphonate inhibitors as novel antimicrobial drugs against Mycobacteria in the lab of David Rice. He stayed in Sheffield for his PhD degree and a short postdoctoral position, in the labs of Stuart Wilson and Ian Sudbery, where he applied next-generation sequencing techniques to study the roles of the nuclear proteins hnRNPU and hnRNPUL1 in regulating gene expression. His scientific interests lie in the cellular roles of non-coding RNAs, chromatin biology, and RNA polymerase II transcription. He is currently exploiting chromatin regulation by fusion oncoproteins to investigate how chromatin architecture influences gene expression.
Yi-Hung is a Graduate Student in the Development, Disease Models & Therapeutics Graduate Program at Baylor College of Medicine. She received her B.S. degree in Pharmacy from Taipei Medical University and her M.S. degree in Pharmacology from National Yang Ming Chiao Tung University in Taiwan where she studied the involvement of RNA m6A modification in EGFR-TKIs resistant lung adenocarcinoma. Yi-Hung joined the University of Houston as a research assistant in Tai-Yen Chen’s lab. Her work focused on establishing a mEos4B-CTR1 knock-in hESCs cell line using CRISPR-Cas9 technology. Before joining Baylor College of Medicine, Yi-Hung was a research assistant at UTHealth where she worked for Dung-Fang Lee studying hereditary retinoblastoma in patient derived iPSC models.
John is a Research Associate at Baylor College of Medicine. John received his B.S. degree in Biochemistry from Texas Tech University and his Ph.D. degree in Biochemistry from the University of North Carolina at Chapel Hill where he worked for Ann Erickson studying lysosomal enzyme trafficking. John continued his training as a postdoctoral fellow in the laboratory of Sandra Lemmon at the University of Miami studying clathrin-mediated endocytosis in Saccharomyces cerevisiae. John returned to Texas upon joining the lab of Michael Lorenz at UTHealth to study virulence traits of the pathogenic fungus Candida albicans. Most recently, he worked with Richard Sifers at Baylor College of Medicine to study proteins and pathways involved in degradation of terminally-misfolded alpha-1-antitrypsin protein.
In 2022, Cate joined Baylor College of Medicine as a Research Technician in the Department of Molecular and Cellular Biology. She graduated from the University of Dayton in 2022 where she received her bachelor’s degree in Biochemistry with a minor in English. Throughout her undergraduate career, she investigated the use of boron dipyrromethene dyes as potential photodynamic therapy agents in the lab of Shawn Swavey.
Quan joined Baylor College of Medicine as a Research Technician in the Department of Molecular and Cellular Biology in 2022. He graduated from Yale University in 2022 where he received his bachelor’s degree in Molecular, Cellular and Developmental Biology, and minor in Statistics and Data Science. As an undergraduate, his research focused on the determination of catalytically independent and protein dependent signaling pathways of ENPP1, the sole human enzyme which generates inorganic pyrophosphate, using transgenic mice models in the lab of Demetrios Braddock.
In 2022, Chris joined the Baylor College of Medicine as a Research Technician in the Department of Molecular and Cellular Biology. He graduated from Kenyon College in 2022 where he received his bachelor’s degree in Molecular Biology. During his undergraduate, he conducted research focusing on the crosstalk between the thyroid hormone pathway and aryl hydrocarbon receptor signaling in a tissue specific manner under the guidance of Wade Powell.
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Alumni
Northwestern University (2017-2021)
Northwestern University (2017-2021)
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2017-2020
2017-2021 2019-2020 2019-2021 2020-2021 2020-2021 |
Haneen Ammouri, Research Technician
Celeste Rosencrance, Research Technician, Graduate Student Qi Yu, Bioinformatics Scientist Tiffany Ge, Graduate Student Jingxiao Zhang, Bioinformatics Scientist Grant Zimmerman, Research Technician |
Currently: Lab Manager, Vanqua Bio
Currently: Graduate Student, Northwestern University Currently: Staff, NIH Currently: Graduate Student, Northwestern University Currently: Bioinformatics Specialist, Qiagen Currently: Medical Student, Midwestern University |
We have openings for postdoctoral fellows, graduate students, and computational biologists interested in problems at the intersection of nuclear organization, chromosome biology, biochemistry, genomics, computational biology, pharmacology and human disease.
Interested applicants should email Kyle, including their CV and a brief description of their research interests.
Interested applicants should email Kyle, including their CV and a brief description of their research interests.