Shuvra Roy joins us from the CSIR-Institute of Genomics and Integrative Biology as a postdoctoral associate! Welcome to the Eagen Lab!

Congratulations to Cate as she starts medical school!

In what is becoming a lab tradition, the lab had a fantastic time at the Houston Rodeo! Feeling adventurous, John, Chris, and Ivo tried the Fruity Pebbles Shrimp Fried Rice in a pineapple bowl.

Krupa Sampat joins us from Boston University as a bioinformatics analyst!  Welcome to the Eagen Lab!

We are excited to have published a collaborative paper with Chris French's lab at Brigham and Women's Hospital in the journal Cancer Research! We identify EZH2, a chromatin regulator that epigenetically silences genes, as a novel vulnerability in NUT carcinoma, that EZH2 suppression of tumor suppressor genes acts in parallel to the activation of oncogenes by the fusion oncoprotein BRD4-NUT, and that combined treatment of mouse models of NUT carcinoma with both an EZH2 inhibitor and a BET inhibitor potently blocks tumor growth and prolongs animal survival. Congratulations to Cate, Chris, and Quan for their contributions to the success of this project! Click here for full text and also see the spotlight commentary on the paper in Cancer Research.

Congratulations to the French Lab at Brigham and Women's Hospital and Harvard Medical School for their new paper "The BRD4–NUT Fusion Alone Drives Malignant Transformation of NUT Carcinoma"! We were happy to contribute to this story! Click here for full text.

The team took a quick break from the lab for lunch at Winnie's in Midtown, Houston!

We had a great time filming a new video to highlight the lab's research! Check it out below.

The Eagen Lab is not deterred by the hot Texas weather! We began with BBQ for lunch at Truth...

...followed by some escape room fun! Some of us made it out!

Ivo Yonchev joins us from the University of Sheffield as a postdoctoral associate! Welcome to the Eagen Lab!

Yi-Hung Chen joins us as a graduate student in the Development, Disease Models & Therapeutics Graduate Program at Baylor College of Medicine!  Welcome to the Eagen Lab!

The lab enjoyed learning about all the exciting science during the 2023 Department of Molecular and Cellular Biology Retreat at the Houston Zoom!

The lab enjoyed some nice March weather and had a great time at Rodeo Houston!

John Collette joins us as a research associate from a neighboring lab at Baylor College of Medicine. Welcome to the Eagen Lab!

The lab had a fun time at the 2022 Department of Molecular and Cellular Biology Halloween Party. The lab took 3rd place in the costume contest and Cate won 1st place in the pie baking competition!

Enjoying the fantastic food scene in Houston, the lab had a great time at Truth BBQ!

Chris Ponne and Quan Le joins us as a research technicians! Chris is from Kenyon College and Quan joins us from Yale University. Welcome to the Eagen Lab!

Cate Hawkins joins us from the University of Dayton as a research technician! Welcome to the Eagen Lab!

Thrilled to contribute a News & Views article on two new exciting papers in Nature Genetics! Highlights includes how BET proteins, BRD4 in particular, contribute to cohesin-dependent chromatin looping and cohesin-independent genome compartmentalization. Click here for full text.