In what is becoming a lab tradition, the lab had a fantastic time at the Houston Rodeo! Feeling adventurous, John, Chris, and Ivo tried the Fruity Pebbles Shrimp Fried Rice in a pineapple bowl.
Adela Yan and Anna Thommen join us as a graduate students in the Genetics & Genomics Program at Baylor College of Medicine! Welcome to the Eagen Lab!
Krupa Sampat joins us from Boston University as a bioinformatics analyst! Welcome to the Eagen Lab!
We are excited to have published a collaborative paper with Chris French's lab at Brigham and Women's Hospital in the journal Cancer Research! We identify EZH2, a chromatin regulator that epigenetically silences genes, as a novel vulnerability in NUT carcinoma, that EZH2 suppression of tumor suppressor genes acts in parallel to the activation of oncogenes by the fusion oncoprotein BRD4-NUT, and that combined treatment of mouse models of NUT carcinoma with both an EZH2 inhibitor and a BET inhibitor potently blocks tumor growth and prolongs animal survival. Congratulations to Cate, Chris, and Quan for their contributions to the success of this project! Click here for full text and also see the spotlight commentary on the paper in Cancer Research.
Congratulations to the French Lab at Brigham and Women's Hospital and Harvard Medical School for their new paper "The BRD4–NUT Fusion Alone Drives Malignant Transformation of NUT Carcinoma"! We were happy to contribute to this story! Click here for full text.
The Eagen Lab is not deterred by the hot Texas weather! We began with BBQ for lunch at Truth... ...followed by some escape room fun! Some of us made it out!
Ivo Yonchev joins us from the University of Sheffield as a postdoctoral associate! Welcome to the Eagen Lab!
Yi-Hung Chen joins us as a graduate student in the Development, Disease Models & Therapeutics Graduate Program at Baylor College of Medicine! Welcome to the Eagen Lab!
The lab enjoyed learning about all the exciting science during the 2023 Department of Molecular and Cellular Biology Retreat at the Houston Zoom!
John Collette joins us as a research associate from a neighboring lab at Baylor College of Medicine. Welcome to the Eagen Lab!
The lab had a fun time at the 2022 Department of Molecular and Cellular Biology Halloween Party. The lab took 3rd place in the costume contest and Cate won 1st place in the pie baking competition!
Chris Ponne and Quan Le joins us as a research technicians! Chris is from Kenyon College and Quan joins us from Yale University. Welcome to the Eagen Lab!
Cate Hawkins joins us from the University of Dayton as a research technician! Welcome to the Eagen Lab!
Thrilled to contribute a News & Views article on two new exciting papers in Nature Genetics! Highlights includes how BET proteins, BRD4 in particular, contribute to cohesin-dependent chromatin looping and cohesin-independent genome compartmentalization. Click here for full text.
Congratulations to the Foltz Lab at Northwestern University for their new paper "UBR7 acts as a histone chaperone for post-nucleosomal histone H3"! We were happy to contribute to this story! Click here for full text.
The lab has completed its move to Houston, is unpacking, and opens its doors at Baylor College of Medicine! We are recruiting for multiple positions at all levels - postdoctoral fellows, graduate students, computational biologist, and research technicians & associates - so please email Kyle if you're interested in joining us!
We are thrilled to announce that the Eagen Lab will be moving to Baylor College of Medicine on November 1, 2021! We will be joining the Department of Molecular and Cellular Biology and will also be affiliated with the Center for Precision Environmental Health, the Stem Cells and Regenerative Medicine Center, and the Center for Cell and Gene Therapy. We are recruiting for multiple positions at all levels, so please contact Kyle if you're interested in joining us! |
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